Mechanogenetics for the remote and noninvasive control of cancer immunotherapy

While cell-based immunotherapy, especially chimeric antigen receptor (CAR)-expressing T cells, is becoming a paradigm-shifting therapeutic approach for cancer treatment, there is a lack of general methods to remotely and noninvasively regulate genetics in live mammalian cells and animals for cancer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Pan, Yijia, Yoon, Sangpil, Sun, Jie, Huang, Ziliang, Lee, Changyang, Allen, Molly, Wu, Yiqian, Chang, Ya-Ju, Sadelain, Michel, Shung, K. Kirk, Chien, Shu, Wang, Yingxiao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2018
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798350/
https://ncbi.nlm.nih.gov/pubmed/29343642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714900115
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