Identification of genes required for Mycobacterium abscessus growth in vivo with a prominent role of the ESX-4 locus

Mycobacterium abscessus, a rapidly growing mycobacterium (RGM) and an opportunistic human pathogen, is responsible for a wide spectrum of clinical manifestations ranging from pulmonary to skin and soft tissue infections. This intracellular organism can resist the bactericidal defense mechanisms of a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Laencina, Laura, Dubois, Violaine, Le Moigne, Vincent, Viljoen, Albertus, Majlessi, Laleh, Pritchard, Justin, Bernut, Audrey, Piel, Laura, Roux, Anne-Laure, Gaillard, Jean-Louis, Lombard, Bérengère, Loew, Damarys, Rubin, Eric J., Brosch, Roland, Kremer, Laurent, Herrmann, Jean-Louis, Girard-Misguich, Fabienne
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798338/
https://ncbi.nlm.nih.gov/pubmed/29343644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713195115
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