Pharmacoimaging of Blood-Brain Barrier Permeable (FDG) and Impermeable (FLT) Substrates After Intranasal (IN) Administration

PURPOSE: To illustrate the use of imaging to quantify the transfer of materials from the nasal cavity to other anatomical compartments, specifically, transfer to the brain using the thymidine analogue, [(18)F]fluorothymidine (FLT), and the glucose analogue, [(18)F]fluorodeoxyglucose (FDG). METHODS:...

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Detaylı Bibliyografya
Yayımlandı:AAPS J
Asıl Yazarlar: Boles Ponto, Laura L., Walsh, Susan, Huang, Jiangeng, Mundt, Christine, Thede-Reynolds, Katherine, Watkins, G. Leonard, Sunderland, John, Acevedo, Michael, Donovan, Maureen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798226/
https://ncbi.nlm.nih.gov/pubmed/29218424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-017-0157-6
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