Fluorine-18-Labeled Thymidine Positron Emission Tomography (FLT-PET) as an Index of Cell Proliferation after Pharmacological Ascorbate-Based Therapy

Pharmacological ascorbate (AscH(−)) induces cytotoxicity and oxidative stress selectively in pancreatic cancer cells compared with normal cells. Positron emission tomography (PET) with the thymidine analog 3′-deoxy-3′-((18)F) fluorothymidine (FLT) enables noninvasive imaging and quantification of th...

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Bibliografiset tiedot
Julkaisussa:Radiat Res
Päätekijät: Cieslak, John A., Sibenaller, Zita A., Walsh, Susan A., Boles Ponto, Laura L., Du, Juan, Sunderland, John J., Cullen, Joseph J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720529/
https://ncbi.nlm.nih.gov/pubmed/26720803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14203.1
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