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TRIP6 inhibits Hippo signaling in response to tension at adherens junctions

The transcriptional co‐activator YAP controls cell proliferation, survival, and tissue regeneration in response to changes in the mechanical environment. It is not known how mechanical stimuli such as tension are sensed and how the signal is transduced to control YAP activity. Here, we show that the...

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Vydáno v:EMBO Rep
Hlavní autoři: Dutta, Shubham, Mana‐Capelli, Sebastian, Paramasivam, Murugan, Dasgupta, Ishani, Cirka, Heather, Billiar, Kris, McCollum, Dannel
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797958/
https://ncbi.nlm.nih.gov/pubmed/29222344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744777
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