Targeting naturally occurring epitope variants of hepatitis C virus with high-affinity T-cell receptors

Hepatitis C virus (HCV) readily establishes chronic infection, which is characterized by failure of virus-specific CD8(+) T cells. HCV uses epitope mutation and T-cell exhaustion to escape from the host immune response. Previously, we engineered high-affinity T-cell receptors (HATs) targeting human...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Gen Virol
Main Authors: Zhang, Huajun, Zhang, Jianbing, Chen, Lei, Weng, Zhiming, Tian, Ye, Zhao, Haifeng, Li, Youjia, Chen, Lin, Liang, Zhaoduan, Zheng, Hongjun, Zhao, Wenzhuo, Zhong, Shi, Li, Yi
Format: Artigo
Sprog:Inglês
Udgivet: Microbiology Society 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797947/
https://ncbi.nlm.nih.gov/pubmed/27902325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000656
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker