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Whole exome sequencing to identify genetic markers for trastuzumab‐induced cardiotoxicity

Although trastuzumab‐induced cardiotoxicity is an important determinant to limit the use of this drug, the molecular mechanism of risk for this toxicity is not well understood. To identify genetic variants determining the risk of trastuzumab‐induced cardiotoxicity, we carried out whole exome sequenc...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Udagawa, Chihiro, Nakamura, Hiromi, Ohnishi, Hiroshi, Tamura, Kenji, Shimoi, Tatsunori, Yoshida, Masayuki, Yoshida, Teruhiko, Totoki, Yasushi, Shibata, Tatsuhiro, Zembutsu, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797809/
https://ncbi.nlm.nih.gov/pubmed/29247589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13471
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