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Regulation of c‐MYC transcriptional activity by transforming growth factor‐beta 1‐stimulated clone 22

c‐MYC stimulates cell proliferation through the suppression of cyclin‐dependent kinase (CDK) inhibitors including P15 (CDKN2B) and P21 (CDKN1A). It also activates E‐box‐mediated transcription of various target genes including telomerase reverse transcriptase (TERT) that is involved in cellular immor...

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Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Zheng, Ling, Suzuki, Hiroyuki, Nakajo, Yuka, Nakano, Akinobu, Kato, Mitsuyasu
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797808/
https://ncbi.nlm.nih.gov/pubmed/29224245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13466
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