The A(2B) Adenosine Receptor Modulates the Epithelial– Mesenchymal Transition through the Balance of cAMP/PKA and MAPK/ERK Pathway Activation in Human Epithelial Lung Cells

The epithelial-mesenchymal transition (EMT) is a complex process in which cell phenotype switches from the epithelial to mesenchymal one. The deregulations of this process have been related with the occurrence of different diseases such as lung cancer and fibrosis. In the last decade, several effort...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Giacomelli, Chiara, Daniele, Simona, Romei, Chiara, Tavanti, Laura, Neri, Tommaso, Piano, Ilaria, Celi, Alessandro, Martini, Claudia, Trincavelli, Maria L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797802/
https://ncbi.nlm.nih.gov/pubmed/29445342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00054
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