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Marfan syndrome; a connective tissue disease at the crossroads of mechanotransduction, TGFβ signaling and cell stemness
Mutations in fibrillin-1 cause Marfan syndrome (MFS), the most common heritable disorder of connective tissue. Fibrillin-1 assemblies (microfibrils and elastic fibers) represent a unique dual-function component of the architectural matrix. The first role is structural for they endow tissues with ten...
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| Udgivet i: | Matrix Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5797509/ https://ncbi.nlm.nih.gov/pubmed/28782645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2017.07.004 |
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