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The anillin-related Int1 protein and the Sep7 septin collaborate to maintain cellular ploidy in Candida albicans
Variation in cell ploidy is a common feature of Candida albicans clinical isolates that are resistant to the antifungal drug fluconazole. Here, we report that the anillin-related protein Int1 interacts with septins for coupling cytokinesis with nuclear segregation. Loss of Int1 results in a rapid di...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5797091/ https://ncbi.nlm.nih.gov/pubmed/29396461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20249-9 |
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