A single nucleotide polymorphism uncovers a novel function for the transcription factor Ace2 during Candida albicans hyphal development.

Candida albicans is a major invasive fungal pathogen in humans. An important virulence factor is its ability to switch between the yeast and hyphal forms, and these filamentous forms are important in tissue penetration and invasion. A common feature for filamentous growth is the ability to inhibit c...

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Autors principals: Diana M Calderón-Noreña, Alberto González-Novo, Sara Orellana-Muñoz, Pilar Gutiérrez-Escribano, Yolanda Arnáiz-Pita, Encarnación Dueñas-Santero, M Belén Suárez, Marie-Elisabeth Bougnoux, Francisco Del Rey, Gavin Sherlock, Christophe d'Enfert, Jaime Correa-Bordes, Carlos R Vázquez de Aldana
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2015-04-01
Col·lecció:PLoS Genetics
Accés en línia:http://europepmc.org/articles/PMC4398349?pdf=render
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