Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer

Colorectal sessile serrated adenoma/polyps (SSA/Ps) are well-known precursors of colorectal cancer (CRC) characterized by BRAF mutation and microsatellite instability. By contrast, the molecular characteristics of traditional serrated adenoma (TSAs) are not fully understood. We analyzed genome-wide...

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Udgivet i:Oncotarget
Main Authors: Aoki, Hironori, Yamamoto, Eiichiro, Takasawa, Akira, Niinuma, Takeshi, Yamano, Hiro-O, Harada, Taku, Matsushita, Hiro-O, Yoshikawa, Kenjiro, Takagi, Ryo, Harada, Eiji, Tanaka, Yoshihito, Yoshida, Yuko, Aoyama, Tomoyuki, Eizuka, Makoto, Yorozu, Akira, Kitajima, Hiroshi, Kai, Masahiro, Sawada, Norimasa, Sugai, Tamotsu, Nakase, Hiroshi, Suzuki, Hiromu
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797007/
https://ncbi.nlm.nih.gov/pubmed/29435136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23523
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