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Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies

A number of folate receptor (FR) targeted small molecular drugs and monoclonal antibodies have been introduced into clinical trials to treat FR positive cancers. Because the therapeutic efficacy of these drugs depends prominently on the level of FR-α expression on the cancer cells, patients have bee...

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Pubblicato in:Oncotarget
Autori principali: Shen, Jiayin, Hu, Yingwen, Putt, Karson S., Singhal, Sunil, Han, Haiyong, Visscher, Daniel W., Murphy, Linda M., Low, Philip S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796989/
https://ncbi.nlm.nih.gov/pubmed/29435118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23321
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