Impact of DLK1-DIO3 imprinted cluster hypomethylation in smoker patients with lung cancer

DNA methylation is important for gene expression and genome stability, and its disruption is thought to play a key role in the initiation and progression of cancer and other diseases. The DLK1-DIO3 cluster has been shown to be imprinted in humans, and some of its components are relevant to diverse p...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Molina-Pinelo, Sonia, Salinas, Ana, Moreno-Mata, Nicolás, Ferrer, Irene, Suarez, Rocío, Andrés-León, Eduardo, Rodríguez-Paredes, Manuel, Gutekunst, Julian, Jantus-Lewintre, Eloisa, Camps, Carlos, Carnero, Amancio, Paz-Ares, Luis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796982/
https://ncbi.nlm.nih.gov/pubmed/29435111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10611
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