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Immunometabolism and PI(3)K Signaling As a Link between IL-2, Foxp3 Expression, and Suppressor Function in Regulatory T Cells

CD4(+) Foxp3(+) regulatory T cells (Tregs) are an essential component of immune homeostasis. Modulation of Treg function has been proposed as a means of treating autoimmune conditions and preventing rejection of organ transplants, although achieving this goal will require a detailed understanding of...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Fan, Martin Y., Turka, Laurence A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796885/
https://ncbi.nlm.nih.gov/pubmed/29434595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00069
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