PI3K signalling

The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role for Pi3K pathway in immune cells. Considerable progress in understanding the r...

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Detalhes bibliográficos
Publicado no:Frontiers Research Topics
Main Authors: Martin Turner, Klaus Okkenhaug, Michael R. Gold
Formato: Livro
Idioma:Inglês
Publicado em: Frontiers Media SA 2015
Assuntos:
R5-920
RC581-607
bic Book Industry Communication::M Medicine
B cell
PI3K/AKT/mTOR
Signal Transduction
T cell
PI3K pathway inhibitors
Acesso em linha:https://directory.doabooks.org/handle/20.500.12854/56255
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