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Increased ethanol drinking in “humanized” mice expressing the mu opioid receptor A118G polymorphism are mediated through sex-specific mechanisms
The A118G single nucleotide polymorphism (SNP) of the mu-opioid receptor gene (Oprm1) has been implicated in mediating the rewarding effects of alcohol. Clinical and preclinical studies suggest that the G allele may confer a genetic vulnerability to alcohol dependence, though it remains unknown whet...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Brain Res Bull |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5796878/ https://ncbi.nlm.nih.gov/pubmed/28780411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2017.07.017 |
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