Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end stage renal disease

Design of Phase III trials in diabetic nephropathy currently requires patients at high risk of progression defined as within three years of a hard end-point (end stage renal disease, 40% loss of estimated glomerular filtration rate, or death). To improve design of these trials, we used natural histo...

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Publicat a:Kidney Int
Autors principals: Yamanouchi, Masayuki, Skupien, Jan, Niewczas, Monika A., Smiles, Adam, Doria, Alessandro, Stanton, Robert C., Galecki, Andrzej, Duffin, Kevin L., Pullen, Nick, Breyer, Matthew D., Bonventre, Joseph V., Warram, James H., Krolewski, Andrzej S.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796779/
https://ncbi.nlm.nih.gov/pubmed/28396115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.02.010
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