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Profile of buparlisib and its potential in the treatment of breast cancer: evidence to date

Alteration of the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin signaling pathway is key for the growth and survival of several cancers, including breast cancer. In addition, dysregulation of PI3K signaling may contribute to resistance to several anticancer agents. PI3K inhi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Breast Cancer (Dove Med Press)
Päätekijät: Criscitiello, Carmen, Viale, Giulia, Curigliano, Giuseppe, Goldhirsch, Aron
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796458/
https://ncbi.nlm.nih.gov/pubmed/29430197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S134641
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