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Profile of buparlisib and its potential in the treatment of breast cancer: evidence to date

Alteration of the phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin signaling pathway is key for the growth and survival of several cancers, including breast cancer. In addition, dysregulation of PI3K signaling may contribute to resistance to several anticancer agents. PI3K inhi...

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Detalhes bibliográficos
Publicado no:Breast Cancer (Dove Med Press)
Main Authors: Criscitiello, Carmen, Viale, Giulia, Curigliano, Giuseppe, Goldhirsch, Aron
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796458/
https://ncbi.nlm.nih.gov/pubmed/29430197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S134641
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