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Microglia and Aging: The Role of the TREM2–DAP12 and CX3CL1-CX3CR1 Axes

Depending on the species, microglial cells represent 5–20% of glial cells in the adult brain. As the innate immune effector of the brain, microglia are involved in several functions: regulation of inflammation, synaptic connectivity, programmed cell death, wiring and circuitry formation, phagocytosi...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Mecca, Carmen, Giambanco, Ileana, Donato, Rosario, Arcuri, Cataldo
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796261/
https://ncbi.nlm.nih.gov/pubmed/29361745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19010318
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