Characterizing Metastatic HER2-Positive Gastric Cancer at the CDH1 Haplotype

The CDH1 gene, coding for the E-cadherin protein, is linked to gastric cancer (GC) susceptibility and tumor invasion. The human epidermal growth factor receptor 2 (HER2) is amplified and overexpressed in a portion of GC. HER2 is an established therapeutic target in metastatic GC (mGC). Trastuzumab,...

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Detaylı Bibliyografya
Yayımlandı:Int J Mol Sci
Asıl Yazarlar: Caggiari, Laura, Miolo, Gianmaria, Buonadonna, Angela, Basile, Debora, Santeufemia, Davide A., Cossu, Antonio, Palmieri, Giuseppe, De Zorzi, Mariangela, Fornasarig, Mara, Alessandrini, Lara, Canzonieri, Vincenzo, Lo Re, Giovanni, Puglisi, Fabio, Steffan, Agostino, Cannizzaro, Renato, De Re, Valli
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795997/
https://ncbi.nlm.nih.gov/pubmed/29295527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19010047
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