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Characterizing Metastatic HER2-Positive Gastric Cancer at the CDH1 Haplotype
The CDH1 gene, coding for the E-cadherin protein, is linked to gastric cancer (GC) susceptibility and tumor invasion. The human epidermal growth factor receptor 2 (HER2) is amplified and overexpressed in a portion of GC. HER2 is an established therapeutic target in metastatic GC (mGC). Trastuzumab,...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5795997/ https://ncbi.nlm.nih.gov/pubmed/29295527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19010047 |
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