Sustained IFN-I Expression during Established Persistent Viral Infection: A “Bad Seed” for Protective Immunity

Type I interferons (IFN-I) are one of the primary immune defenses against viruses. Similar to all other molecular mechanisms that are central to eliciting protective immune responses, IFN-I expression is subject to homeostatic controls that regulate cytokine levels upon clearing the infection. Howev...

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Vydáno v:Viruses
Hlavní autoři: Dagenais-Lussier, Xavier, Loucif, Hamza, Murira, Armstrong, Laulhé, Xavier, Stäger, Simona, Lamarre, Alain, van Grevenynghe, Julien
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795425/
https://ncbi.nlm.nih.gov/pubmed/29301196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10010012
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