Type I Interferon Impairs Specific Antibody Responses Early during Establishment of LCMV Infection

Elicitation of type I interferon (IFN-I) has been shown to both enhance and impair cell-mediated immune responses in acute and persistent viral infections, respectively. Here, we show that, in addition to its effect on T cells, IFN-I drives impairment of specific antibody responses through interacti...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Daugan, Matthieu, Murira, Armstrong, Mindt, Barbara C., Germain, Amélie, Tarrab, Esther, Lapierre, Pascal, Fritz, Jörg H., Lamarre, Alain
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136549/
https://ncbi.nlm.nih.gov/pubmed/27994594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00564
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