Lipid homeostasis and inflammatory activation are disturbed in classically activated macrophages with peroxisomal β‐oxidation deficiency

Macrophage activation is characterized by pronounced metabolic adaptation. Classically activated macrophages show decreased rates of mitochondrial fatty acid oxidation and oxidative phosphorylation and acquire a glycolytic state together with their pro‐inflammatory phenotype. In contrast, alternativ...

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Bibliografski detalji
Izdano u:Immunology
Glavni autori: Geric, Ivana, Tyurina, Yulia Y., Krysko, Olga, Krysko, Dmitri V., De Schryver, Evelyn, Kagan, Valerian E., Van Veldhoven, Paul P., Baes, Myriam, Verheijden, Simon
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795189/
https://ncbi.nlm.nih.gov/pubmed/28940384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12844
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