The Pseudomonas aeruginosa ExoY phenotype of high-copy-number recombinants is not detectable in natural isolates

The nucleotidyl cyclase ExoY is an effector protein of the type III secretion system of Pseudomonas aeruginosa. We compared the cyclic nucleotide production and lung disease phenotypes caused by the ExoY-overexpressing strain PA103ΔexoUexoT::Tc pUCPexoY, its vector control strain PA103ΔexoUexoT::Tc...

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Bibliografiske detaljer
Udgivet i:Open Biol
Main Authors: Munder, Antje, Rothschuh, Justin, Schirmer, Bastian, Klockgether, Jens, Kaever, Volkhard, Tümmler, Burkhard, Seifert, Roland, Kloth, Christina
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795057/
https://ncbi.nlm.nih.gov/pubmed/29386405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.170250
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