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ATP12A promotes mucus dysfunction during Type 2 airway inflammation

Allergic airway disease is known to cause significant morbidity due to impaired mucociliary clearance, however the mechanism that leads to the mucus dysfunction is not entirely understood. Interleukin 13 (IL-13), a key mediator of Type 2 (T2) inflammation, profoundly alters the ion transport propert...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lennox, Alison T., Coburn, Stefanie L., Leech, John A., Heidrich, Elisa M., Kleyman, Thomas R., Wenzel, Sally E., Pilewski, Joseph M., Corcoran, Timothy E., Myerburg, Mike M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794982/
https://ncbi.nlm.nih.gov/pubmed/29391451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20444-8
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