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Dysregulated fibronectin trafficking by Hsp90 inhibition restricts prostate cancer cell invasion
The molecular chaperone Hsp90 is overexpressed in prostate cancer (PCa) and is responsible for the folding, stabilization and maturation of multiple oncoproteins, which are implicated in PCa progression. Compared to first-in-class Hsp90 inhibitors such as 17-allylamino-demethoxygeldanamycin (17-AAG)...
שמור ב:
| הוצא לאור ב: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5794796/ https://ncbi.nlm.nih.gov/pubmed/29391407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19871-4 |
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