SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses

The human interferon (IFN)-induced MxA protein is a key antiviral host restriction factor exhibiting broad antiviral activity against many RNA viruses, including highly pathogenic avian influenza A viruses (IAV) of the H5N1 and H7N7 subtype. To date the mechanism for how MxA exerts its antiviral act...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dornfeld, Dominik, Dudek, Alexandra H., Vausselin, Thibaut, Günther, Sira C., Hultquist, Judd F., Giese, Sebastian, Khokhlova-Cubberley, Daria, Chew, Yap C., Pache, Lars, Krogan, Nevan J., Garcia-Sastre, Adolfo, Schwemmle, Martin, Shaw, Megan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794779/
https://ncbi.nlm.nih.gov/pubmed/29391557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20458-2
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