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Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import
To establish a new lineage in the human population, avian influenza A viruses (AIV) must overcome the intracellular restriction factor MxA. Partial escape from MxA restriction can be achieved when the viral nucleoprotein (NP) acquires the critical human-adaptive amino acid residues 100I/V, 283P, and...
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| Izdano u: | Sci Rep |
|---|---|
| Glavni autori: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4796820/ https://ncbi.nlm.nih.gov/pubmed/26988202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23138 |
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