Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA

Venous thromboembolic (VTE) disease, consisting of deep venous thrombosis (DVT) and pulmonary embolism (PE) is a leading cause of morbidity and mortality. Current prophylactic measures are insufficient to prevent all occurrence in part due to an incomplete understanding of the underlying pathophysio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dyer, Mitchell R., Chen, Qiwei, Haldeman, Shannon, Yazdani, Hamza, Hoffman, Rosemary, Loughran, Patricia, Tsung, Allan, Zuckerbraun, Brian S., Simmons, Richard L., Neal, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794752/
https://ncbi.nlm.nih.gov/pubmed/29391442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20479-x
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