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BMP3 expression by osteoblast lineage cells is regulated by canonical Wnt signaling

Bone morphogenetic protein (BMP) and canonical Wnt (cWnt) signaling factors are both known to regulate bone mass, fracture risk, fracture repair, and osteoblastogenesis. BMP3 is the most abundant BMP and negatively regulates osteoblastogenesis and bone mass. Thus, identifying the mechanism by which...

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Detalles Bibliográficos
Publicado en:FEBS Open Bio
Main Authors: Kokabu, Shoichiro, Rosen, Vicki
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794463/
https://ncbi.nlm.nih.gov/pubmed/29435407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12347
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