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Diverse functions of homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence

β‐ and γ‐cytoplasmic actin are nearly indistinguishable in their amino acid sequence, but are encoded by different genes that play non‐redundant biological roles. The key determinants that drive their functional distinction are unknown. Here, we tested the hypothesis that β- and γ-actin functions ar...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Vedula, Pavan, Kurosaka, Satoshi, Leu, Nicolae Adrian, Wolf, Yuri I, Shabalina, Svetlana A, Wang, Junling, Sterling, Stephanie, Dong, Dawei W, Kashina, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794254/
https://ncbi.nlm.nih.gov/pubmed/29244021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31661
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