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Diverse functions of homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence

β‐ and γ‐cytoplasmic actin are nearly indistinguishable in their amino acid sequence, but are encoded by different genes that play non‐redundant biological roles. The key determinants that drive their functional distinction are unknown. Here, we tested the hypothesis that β- and γ-actin functions ar...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Vedula, Pavan, Kurosaka, Satoshi, Leu, Nicolae Adrian, Wolf, Yuri I, Shabalina, Svetlana A, Wang, Junling, Sterling, Stephanie, Dong, Dawei W, Kashina, Anna
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794254/
https://ncbi.nlm.nih.gov/pubmed/29244021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31661
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