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Adipocyte/breast cancer cell crosstalk in obesity interferes with the anti-proliferative efficacy of tamoxifen

BACKGROUND: Obesity is a well-known risk factor of breast cancer in post-menopausal women that also correlates with a diminished therapeutic response. The influence of adipocytes and their secretome, i.e. adipokines, on the efficacy of hormone therapy has yet to be elucidated. METHODS: We investigat...

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הוצא לאור ב:	PLoS One
Main Authors:	Bougaret, Lauriane, Delort, Laetitia, Billard, Hermine, Le Huede, Camille, Boby, Céline, De la Foye, Anne, Rossary, Adrien, Mojallal, Ali, Damour, Odile, Auxenfans, Céline, Vasson, Marie Paule, Caldefie-Chezet, Florence
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Public Library of Science 2018
נושאים:	Research Article
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5794086/ https://ncbi.nlm.nih.gov/pubmed/29389973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191571
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Adipocyte/breast cancer cell crosstalk in obesity interferes with the anti-proliferative efficacy of tamoxifen

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