Adipocyte/breast cancer cell crosstalk in obesity interferes with the anti-proliferative efficacy of tamoxifen

BACKGROUND: Obesity is a well-known risk factor of breast cancer in post-menopausal women that also correlates with a diminished therapeutic response. The influence of adipocytes and their secretome, i.e. adipokines, on the efficacy of hormone therapy has yet to be elucidated. METHODS: We investigat...

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Veröffentlicht in:PLoS One
Hauptverfasser: Bougaret, Lauriane, Delort, Laetitia, Billard, Hermine, Le Huede, Camille, Boby, Céline, De la Foye, Anne, Rossary, Adrien, Mojallal, Ali, Damour, Odile, Auxenfans, Céline, Vasson, Marie Paule, Caldefie-Chezet, Florence
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794086/
https://ncbi.nlm.nih.gov/pubmed/29389973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191571
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