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Structure of the human myostatin precursor and determinants of growth factor latency
Myostatin, a key regulator of muscle mass in vertebrates, is biosynthesised as a latent precursor in muscle and is activated by sequential proteolysis of the pro‐domain. To investigate the molecular mechanism by which pro‐myostatin remains latent, we have determined the structure of unprocessed pro‐...
Gorde:
| Argitaratua izan da: | EMBO J |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
John Wiley and Sons Inc.
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5793801/ https://ncbi.nlm.nih.gov/pubmed/29330193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797883 |
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