Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome

Understanding transcriptome complexity is crucial for understanding human biology and disease. Technologies such as Synthetic long-read RNA sequencing (SLR-RNA-seq) delivered 5 million isoforms and allowed assessing splicing coordination. Pacific Biosciences and Oxford Nanopore increase throughput a...

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Detaylı Bibliyografya
Yayımlandı:Genome Res
Asıl Yazarlar: Tilgner, Hagen, Jahanbani, Fereshteh, Gupta, Ishaan, Collier, Paul, Wei, Eric, Rasmussen, Morten, Snyder, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2018
Konular:
Method
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793787/
https://ncbi.nlm.nih.gov/pubmed/29196558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.230516.117
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