Comprehensive transcriptome analysis using synthetic long-read sequencing reveals molecular co-association of distant splicing events

Alternative splicing shapes mammalian transcriptomes, with many RNA molecules undergoing multiple distant alternative splicing events. Comprehensive transcriptome analysis, including analysis of exon co-association in the same molecule, requires deep, long-read sequencing. Here we introduce an RNA s...

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Vydáno v:Nat Biotechnol
Hlavní autoři: Tilgner, Hagen, Jahanbani, Fereshteh, Blauwkamp, Tim, Moshrefi, Ali, Jaeger, Erich, Chen, Feng, Harel, Itamar, Bustamante, Carlos D, Rasmussen, Morten, Snyder, Michael P
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832928/
https://ncbi.nlm.nih.gov/pubmed/25985263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3242
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