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Defining a personal, allele-specific, and single-molecule long-read transcriptome

Personal transcriptomes in which all of an individual’s genetic variants (e.g., single nucleotide variants) and transcript isoforms (transcription start sites, splice sites, and polyA sites) are defined and quantified for full-length transcripts are expected to be important for understanding individ...

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Bibliographic Details
Main Authors: Tilgner, Hagen, Grubert, Fabian, Sharon, Donald, Snyder, Michael P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103364/
https://ncbi.nlm.nih.gov/pubmed/24961374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400447111
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