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Defining a personal, allele-specific, and single-molecule long-read transcriptome

Personal transcriptomes in which all of an individual’s genetic variants (e.g., single nucleotide variants) and transcript isoforms (transcription start sites, splice sites, and polyA sites) are defined and quantified for full-length transcripts are expected to be important for understanding individ...

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Bibliografiske detaljer
Main Authors: Tilgner, Hagen, Grubert, Fabian, Sharon, Donald, Snyder, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103364/
https://ncbi.nlm.nih.gov/pubmed/24961374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400447111
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