A novel role of ER stress signal transducer ATF6 in regulating enterovirus A71 viral protein stability

BACKGROUND: Due to limited coding capacity of viral genome, enterovirus A71 (EV-A71) co-opts host nuclear proteins for its replication. Upon ER stress, the ER-localized 90 kDa activating transcription factor 6 (p90ATF6) is proteolytically cleaved to produce the transcriptionally active amino-termina...

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Detaylı Bibliyografya
Yayımlandı:J Biomed Sci
Asıl Yazarlar: Jheng, Jia-Rong, Lau, Kean-Seng, Lan, Yueh-Wen, Horng, Jim-Tong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793394/
https://ncbi.nlm.nih.gov/pubmed/29386036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-018-0412-x
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