Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment

Radiotherapy (RT) enhances innate and adaptive antitumor immunity; however, the effects of radiation on suppressive immune cells, such as regulatory T cells (Treg), in the tumor microenvironment (TME) are not fully elucidated. Although previous reports suggest an increased Treg infiltration after ra...

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Veröffentlicht in:Cancer Immunol Res
Hauptverfasser: Muroyama, Yuki, Nirschl, Thomas R., Kochel, Christina M., Lopez-Bujanda, Zoila, Theodros, Debebe, Mao, Wendy, Carrera-Haro, Maria A., Ghasemzadeh, Ali, Marciscano, Ariel E., Velarde, Esteban, Tam, Ada J., Thoburn, Christopher J., Uddin, Muniza, Meeker, Alan K., Anders, Robert A., Pardoll, Drew M., Drake, Charles G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793220/
https://ncbi.nlm.nih.gov/pubmed/28970196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0040
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