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Wnt, RSPO and Hippo Signalling in the Intestine and Intestinal Stem Cells
In this review, we address aspects of Wnt, R-Spondin (RSPO) and Hippo signalling, in both healthy and transformed intestinal epithelium. In intestinal stem cells (ISCs), the Wnt pathway is essential for intestinal crypt formation and renewal, whereas RSPO-mediated signalling mainly affects ISC numbe...
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| 發表在: | Genes (Basel) |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5793173/ https://ncbi.nlm.nih.gov/pubmed/29316729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9010020 |
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