Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity

The Wnt pathway plays a crucial role in self‐renewal and differentiation of cells in the adult gut. In the present study, we revealed the functional consequences of inhibition of canonical Wnt signaling in the intestinal epithelium. The study was based on generation of a novel transgenic mouse strai...

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Detalhes bibliográficos
Publicado no:Genesis
Main Authors: Janeckova, Lucie, Fafilek, Bohumil, Krausova, Michaela, Horazna, Monika, Vojtechova, Martina, Alberich‐Jorda, Meritxell, Sloncova, Eva, Galuskova, Katerina, Sedlacek, Radislav, Anderova, Miroslava, Korinek, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067622/
https://ncbi.nlm.nih.gov/pubmed/26864984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22922
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