Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity

The Wnt pathway plays a crucial role in self‐renewal and differentiation of cells in the adult gut. In the present study, we revealed the functional consequences of inhibition of canonical Wnt signaling in the intestinal epithelium. The study was based on generation of a novel transgenic mouse strai...

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Опубликовано в: :Genesis
Главные авторы: Janeckova, Lucie, Fafilek, Bohumil, Krausova, Michaela, Horazna, Monika, Vojtechova, Martina, Alberich‐Jorda, Meritxell, Sloncova, Eva, Galuskova, Katerina, Sedlacek, Radislav, Anderova, Miroslava, Korinek, Vladimir
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067622/
https://ncbi.nlm.nih.gov/pubmed/26864984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22922
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