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Serendipitous Discovery of a Guanine-rich DNA Molecule with a Highly Stable Structure in Urea
We have made an accidental discovery of an unusual, single-stranded, guanine-rich DNA molecule that is capable of adopting a folded structure in 7 M urea (7MU) known to denature nucleic acid structures. The folding of this molecule requires Na(+) and Mg(2+) and the folded structure remains stable wh...
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| 發表在: | Sci Rep |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5792554/ https://ncbi.nlm.nih.gov/pubmed/29386529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20248-w |
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