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Effect of ovariectomy on intracellular Ca(2+) regulation in guinea pig cardiomyocytes

This study addressed the hypothesis that long-term deficiency of ovarian hormones after ovariectomy (OVx) alters cellular Ca(2+)-handling mechanisms in the heart, resulting in the formation of a proarrhythmic substrate. It also tested whether estrogen supplementation to OVx animals reverses any alte...

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Detalles Bibliográficos
Publicado en:Am J Physiol Heart Circ Physiol
Autores principales: Yang, Hsiang-Yu, Firth, Jahn M., Francis, Alice J., Alvarez-Laviada, Anita, MacLeod, Kenneth T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792202/
https://ncbi.nlm.nih.gov/pubmed/28778911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00249.2017
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