Endothelial cell senescence with aging in healthy humans: prevention by habitual exercise and relation to vascular endothelial function

Cellular senescence is emerging as a key mechanism of age-related vascular endothelial dysfunction, but evidence in healthy humans is lacking. Moreover, the influence of lifestyle factors such as habitual exercise on endothelial cell (EC) senescence is unknown. We tested the hypothesis that EC senes...

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Vydáno v:Am J Physiol Heart Circ Physiol
Hlavní autoři: Rossman, Matthew J., Kaplon, Rachelle E., Hill, Sierra D., McNamara, Molly N., Santos-Parker, Jessica R., Pierce, Gary L., Seals, Douglas R., Donato, Anthony J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2017
Témata:
Rapid Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792201/
https://ncbi.nlm.nih.gov/pubmed/28971843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00416.2017
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